In the particular case of an ssh proxy running, connected to something like ssh -D 4321 blah.com
google-chrome --proxy-server="socks5://127.0.0.1:4321" --host-resolver-rules="MAP * 0.0.0.0 , EXCLUDE 127.0.0.1"
OSX
/Applications/Google\ Chrome.app/Contents/MacOSogle\ Chrome --proxy-server="socks5://127.0.0.1:4321" --host-resolver-rules="MAP * 0.0.0.0 , EXCLUDE 127.0.0.1"